Beta
Acetaminophen
medicationPain reliever and fever reducer (brand name: Tylenol). Does not reduce inflammation. Available OTC.
Reported Benefits
Acetaminophen for Prevention and Treatment of Organ Dysfunction in Critically Ill Patients With Sepsis: The ASTER Randomized Clinical Trial.
Not specified in source
A randomized clinical trial of 447 adults with sepsis found acetaminophen was safe with no difference in liver enzymes, hypotension, or fluid balance compared to placebo, though days alive and free of organ support were not meaningfully different between groups (20.2 vs 19.6 days).
Reported Side Effects
Mount Sinai Study Supports Evidence That Prenatal Acetaminophen Use May Be Linked to Increased Risk of Autism and ADHD
Mount Sinai research team
A meta-analysis of 46 studies incorporating data from over 100,000 participants found associations between prenatal acetaminophen use and increased risk of autism and ADHD in offspring, though researchers emphasize the need for caution and further study.
Evaluation of the Evidence on Acetaminophen Use and Neurodevelopmental Disorders
Not specified in source
A systematic review found that the majority of studies reported positive associations between prenatal acetaminophen use and ADHD, autism spectrum disorder, or neurodevelopmental disorders in offspring.
Acetaminophen May Be Less Heart-safe than Previously Thought
Gabriela Rivera, Aldrin Gomes
A mouse study found that regular acetaminophen use at concentrations considered safe (equivalent to 500 mg/day) altered over 20 different signaling pathways in heart tissue, affecting energy production, antioxidant usage, and protein breakdown.
Related health conditions
Research showing how this habit affects specific health conditions. Always consult healthcare professionals.
May Worsen
Attention-Deficit/Hyperactivity Disorder affecting focus, impulse control, and executive function
Mount Sinai Study Supports Evidence That Prenatal Acetaminophen Use May Be Linked to Increased Risk of Autism and ADHD
Mount Sinai research team
A meta-analysis of 46 studies incorporating data from over 100,000 participants found associations between prenatal acetaminophen use and increased risk of autism and ADHD in offspring, though researchers emphasize the need for caution and further study.
Evaluation of the Evidence on Acetaminophen Use and Neurodevelopmental Disorders
Not specified in source
A systematic review found that the majority of studies reported positive associations between prenatal acetaminophen use and ADHD, autism spectrum disorder, or neurodevelopmental disorders in offspring.
Research (4 studies)
Community updates
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