Drospirenone
medication Under reviewA progestin and antiandrogen medication primarily used in hormonal contraceptives to prevent pregnancy.
Research summary
The best human evidence for drospirenone comes from contraceptive studies in healthy women rather than from supplement-style use. Clinical trials and reviews suggest it can reduce estrogen-related fluid retention and may have a neutral to favorable effect on blood pressure in some groups, while also showing antiandrogenic benefits that can improve acne. Some studies also suggest favorable effects on bone markers and vitamin D status in users of drospirenone-containing oral contraceptives. The main safety concern documented in human observational literature is an increased risk of venous thromboembolism with some drospirenone-containing combined oral contraceptives compared with levonorgestrel-containing pills. Because drospirenone is a prescription hormone, the overall evidence base is strongest for contraceptive and hormonal-use outcomes, not for general wellness supplementation.
Reported Benefits
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Added benefits of drospirenone for compliance.
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Pharmacological and metabolic effects of drospirenone as a progestogen in hormone therapy
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LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women
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Pharmacological and metabolic effects of drospirenone as a progestogen in hormone therapy
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Drospirenone: Uses, Interactions, Mechanism of Action
DrugBank
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Drospirenone: Uses, Interactions, Mechanism of Action
DrugBank
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Drospirenone: Uses, Interactions, Mechanism of Action
DrugBank
Reported Side Effects
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Progestin-Only (drospirenone) Oral Contraceptives
MedlinePlus
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Progestin-Only (drospirenone) Oral Contraceptives
MedlinePlus
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Progestin-Only (drospirenone) Oral Contraceptives
MedlinePlus
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Progestin-Only (drospirenone) Oral Contraceptives
MedlinePlus
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Progestin-Only (drospirenone) Oral Contraceptives
MedlinePlus
No reports yet
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Progestin-Only (drospirenone) Oral Contraceptives
MedlinePlus
No reports yet
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Progestin-Only (drospirenone) Oral Contraceptives
MedlinePlus
Related health conditions
Research showing how this habit affects specific health conditions. Always consult healthcare professionals.
May Help With
Skin condition causing pimples, blackheads, and cysts
Drospirenone: Uses, Interactions, Mechanism of Action
DrugBank
Research (5 studies)
Drospirenone: Uses, Interactions, Mechanism of Action
DrugBank
Progestin-Only (drospirenone) Oral Contraceptives
MedlinePlus
Pharmacological and metabolic effects of drospirenone as a progestogen in hormone therapy
Not specified in search result
LF111 or Drospirenone Chew vs Non-hormonal Contraceptive Methods on Bone Mineral Density in Adolescent and Adult Women
Not specified in search result
Added benefits of drospirenone for compliance.
Not specified in search result
Community updates
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