Progesterone
medicationHormone used in HRT alongside estrogen. Helps protect uterine lining and supports sleep.
Reported Benefits
Progesterone and human cognition.
Barth C et al.
Progesterone levels positively associated with verbal memory and global cognition in healthy women, though trial results in postmenopausal hormone therapy showed minimal cognitive differences versus placebo.
Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial: Endometrial Protection and Cardiovascular Effects
The Writing Group for the PEPI Trial
Micronized progesterone effectively protected the endometrium from hyperplastic changes in postmenopausal women on estrogen therapy, with no increase in blood pressure and minimal impact on estrogen's HDL benefits compared to placebo.
Progesterone therapy, endothelial function and cardiovascular risk factors: a 3-month randomized, placebo-controlled trial in healthy early postmenopausal women.
Prior JC et al.
Oral micronized progesterone in recently postmenopausal women preserved endothelial function, showed no changes in blood pressure, weight, inflammation, or coagulation, and had short-term cardiovascular safety comparable to placebo despite a small HDL-C decrease.
Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial: Endometrial Protection and Cardiovascular Effects
The Writing Group for the PEPI Trial
Micronized progesterone effectively protected the endometrium from hyperplastic changes in postmenopausal women on estrogen therapy, with no increase in blood pressure and minimal impact on estrogen's HDL benefits compared to placebo.
Progesterone therapy, endothelial function and cardiovascular risk factors: a 3-month randomized, placebo-controlled trial in healthy early postmenopausal women.
Prior JC et al.
Oral micronized progesterone in recently postmenopausal women preserved endothelial function, showed no changes in blood pressure, weight, inflammation, or coagulation, and had short-term cardiovascular safety comparable to placebo despite a small HDL-C decrease.
Progesterone therapy, endothelial function and cardiovascular risk factors: a 3-month randomized, placebo-controlled trial in healthy early postmenopausal women.
Prior JC et al.
Oral micronized progesterone in recently postmenopausal women preserved endothelial function, showed no changes in blood pressure, weight, inflammation, or coagulation, and had short-term cardiovascular safety comparable to placebo despite a small HDL-C decrease.
No side effects tracked yet
No side effects have been reported by studies or users for this habit yet.
Research (3 studies)
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