Beta
Semaglutide
medicationGLP-1 receptor agonist (brand names: Ozempic, Wegovy). Used for type 2 diabetes and weight management. Weekly injection.
Reported Benefits
PIONEER 1: Randomized Clinical Trial of the Efficacy and Safety of Once-Daily Oral Semaglutide With, Without, or in Combination With Metformin in Patients With Type 2 Diabetes
Ahrén B, Masmiquelle C, Freyche S, et al.
Oral semaglutide doses of 7 mg and 14 mg reduced body weight compared to placebo in adults with type 2 diabetes inadequately controlled by diet and exercise, with the 14 mg dose showing superior weight loss.
Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial.
Wilding JPH, Batterham RL, Calanna S, et al.
In adults with overweight or obesity who achieved initial weight loss during a 20-week run-in with semaglutide 2.4 mg, continued treatment led to further mean weight loss of 7.9% over 48 weeks versus 6.9% regain with placebo, alongside reductions in waist circumference, blood pressure, and improvements in physical functioning.
Semaglutide for the treatment of overweight and obesity: A review
Wilding JPH, et al.
Semaglutide 2.4 mg weekly was associated with mean weight losses of 14.9%-17.4% from baseline in individuals with overweight or obesity without type 2 diabetes.
Reported Side Effects
Compounded Semaglutide and Tirzepatide Products Use Unique Formulations but Efficacy and Safety Largely Unknown.
Hussain Z, Khan JA
Semaglutide treatment across multiple trials induced mostly mild-to-moderate transient gastrointestinal disturbances and increased risk of biliary disease.
Compounded Semaglutide and Tirzepatide Products Use Unique Formulations but Efficacy and Safety Largely Unknown.
Hussain Z, Khan JA
Semaglutide treatment across multiple trials induced mostly mild-to-moderate transient gastrointestinal disturbances and increased risk of biliary disease.
Related health conditions
Research showing how this habit affects specific health conditions. Always consult healthcare professionals.
May Help With
Metabolic disorder characterized by high blood sugar
PIONEER 1: Randomized Clinical Trial of the Efficacy and Safety of Once-Daily Oral Semaglutide With, Without, or in Combination With Metformin in Patients With Type 2 Diabetes
Ahrén B, Masmiquelle C, Freyche S, et al.
Oral semaglutide doses of 7 mg and 14 mg reduced body weight compared to placebo in adults with type 2 diabetes inadequately controlled by diet and exercise, with the 14 mg dose showing superior weight loss.
Research (4 studies)
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