Baby Aspirin
medicationLow-dose aspirin (81mg) for cardiovascular protection. Often prescribed for heart attack/stroke prevention. Available OTC but should be taken under medical guidance.
Reported Benefits
Effect of Aspirin on All-Cause Mortality in the Healthy Elderly.
McNeil JJ, Wolfe R, Woods RL, et al.
In 19,114 healthy older adults without prior cardiovascular events, daily 100 mg aspirin did not reduce all-cause mortality, cardiovascular events, or disability-free survival compared to placebo over 4.7 years; it increased major bleeding risk.
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus
ASCEND Study Collaborative Group; Bowman L, Mafham M, et al.
In 15,480 adults with diabetes but no prior cardiovascular events, daily 100 mg aspirin reduced serious vascular events by 12% versus placebo but increased major bleeding by 29%, with net benefit uncertain in lower-risk subgroups.
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Gaziano JM, Brotons C, Coppolecchia R, et al.
In 12,546 healthy adults aged 55+ at moderate cardiovascular risk without prior events, daily 100 mg aspirin did not significantly reduce composite cardiovascular events compared to placebo but increased gastrointestinal bleeding.
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus
ASCEND Study Collaborative Group; Bowman L, Mafham M, et al.
In 15,480 adults with diabetes but no prior cardiovascular events, daily 100 mg aspirin reduced serious vascular events by 12% versus placebo but increased major bleeding by 29%, with net benefit uncertain in lower-risk subgroups.
Reported Side Effects
Effect of Aspirin on All-Cause Mortality in the Healthy Elderly.
McNeil JJ, Wolfe R, Woods RL, et al.
In 19,114 healthy older adults without prior cardiovascular events, daily 100 mg aspirin did not reduce all-cause mortality, cardiovascular events, or disability-free survival compared to placebo over 4.7 years; it increased major bleeding risk.
Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus
ASCEND Study Collaborative Group; Bowman L, Mafham M, et al.
In 15,480 adults with diabetes but no prior cardiovascular events, daily 100 mg aspirin reduced serious vascular events by 12% versus placebo but increased major bleeding by 29%, with net benefit uncertain in lower-risk subgroups.
Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial.
Gaziano JM, Brotons C, Coppolecchia R, et al.
In 12,546 healthy adults aged 55+ at moderate cardiovascular risk without prior events, daily 100 mg aspirin did not significantly reduce composite cardiovascular events compared to placebo but increased gastrointestinal bleeding.
Research (3 studies)
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