Beta
NAC
supplementN-acetylcysteine (NAC) is a supplement form of the amino acid cysteine.
Reported Benefits
NAC supplementation and immune function restoration
Not specified
Two studies demonstrated that NAC supplementation significantly enhanced immune function and nearly fully restored natural killer (NK) cell activity in subjects with immune deficiencies.
NAC administration in schizophrenia symptom improvement
Sepehrmanesh et al.
Administration of 1200 mg NAC daily showed positive impact on positive, negative, general, and total psychopathological symptoms in schizophrenia patients, along with improvement of cognitive performance.
High dose N-acetylcysteine on air trapping and airway resistance of chronic obstructive pulmonary disease (HIACE trial)
Not specified
A double-blinded, randomized, placebo-controlled trial with 120 COPD patients (58 treated with 600 mg NAC twice daily, 62 placebo) demonstrated significant improvement in small airway function and reduction in disease exacerbation frequency.
Optimal exercise dose and type for improving schizophrenia symptoms in adults: A systematic review and Bayesian network meta-analysis.
Not specified
Meta-analysis showed that NAC administered for 24 weeks or more improves schizophrenia symptoms and cognitive domain of working memory, with daily doses ranging from 600-3600 mg.
NAC administration in schizophrenia symptom improvement
Sepehrmanesh et al.
Administration of 1200 mg NAC daily showed positive impact on positive, negative, general, and total psychopathological symptoms in schizophrenia patients, along with improvement of cognitive performance.
Optimal exercise dose and type for improving schizophrenia symptoms in adults: A systematic review and Bayesian network meta-analysis.
Not specified
Meta-analysis showed that NAC administered for 24 weeks or more improves schizophrenia symptoms and cognitive domain of working memory, with daily doses ranging from 600-3600 mg.
NAC administration in schizophrenia symptom improvement
Sepehrmanesh et al.
Administration of 1200 mg NAC daily showed positive impact on positive, negative, general, and total psychopathological symptoms in schizophrenia patients, along with improvement of cognitive performance.
Optimal exercise dose and type for improving schizophrenia symptoms in adults: A systematic review and Bayesian network meta-analysis.
Not specified
Meta-analysis showed that NAC administered for 24 weeks or more improves schizophrenia symptoms and cognitive domain of working memory, with daily doses ranging from 600-3600 mg.
NAC supplementation and immune function restoration
Not specified
Two studies demonstrated that NAC supplementation significantly enhanced immune function and nearly fully restored natural killer (NK) cell activity in subjects with immune deficiencies.
NAC effects on homocysteine levels in healthy volunteers
Not specified
Uncontrolled studies in healthy volunteers showed significant homocysteine-lowering effects with acute NAC administration of 7200 mg within 24 hours (44% reduction) and 1200-4000 mg single doses (22% reduction).
High dose N-acetylcysteine on air trapping and airway resistance of chronic obstructive pulmonary disease (HIACE trial)
Not specified
A double-blinded, randomized, placebo-controlled trial with 120 COPD patients (58 treated with 600 mg NAC twice daily, 62 placebo) demonstrated significant improvement in small airway function and reduction in disease exacerbation frequency.
Reported Side Effects
High dose N-acetylcysteine on air trapping and airway resistance of chronic obstructive pulmonary disease (HIACE trial)
Not specified
A double-blinded, randomized, placebo-controlled trial with 120 COPD patients (58 treated with 600 mg NAC twice daily, 62 placebo) demonstrated significant improvement in small airway function and reduction in disease exacerbation frequency.
High dose N-acetylcysteine on air trapping and airway resistance of chronic obstructive pulmonary disease (HIACE trial)
Not specified
A double-blinded, randomized, placebo-controlled trial with 120 COPD patients (58 treated with 600 mg NAC twice daily, 62 placebo) demonstrated significant improvement in small airway function and reduction in disease exacerbation frequency.
High dose N-acetylcysteine on air trapping and airway resistance of chronic obstructive pulmonary disease (HIACE trial)
Not specified
A double-blinded, randomized, placebo-controlled trial with 120 COPD patients (58 treated with 600 mg NAC twice daily, 62 placebo) demonstrated significant improvement in small airway function and reduction in disease exacerbation frequency.
Related health conditions
Research showing how this habit affects specific health conditions. Always consult healthcare professionals.
May Help With
Polycystic Ovary Syndrome - hormonal disorder in women
NAC effects on homocysteine levels in healthy volunteers
Not specified
Uncontrolled studies in healthy volunteers showed significant homocysteine-lowering effects with acute NAC administration of 7200 mg within 24 hours (44% reduction) and 1200-4000 mg single doses (22% reduction).
Research (5 studies)
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