TMG
supplementTMG supports methylation and cardiovascular health.
Reported Benefits
Effect of 6 weeks' betaine supplementation on performance in trained male athletes
Cholewa JM, Guimarães-Ferreira L, Zanchi NE
Randomized trial in 23 healthy trained male athletes showed 2.5g TMG twice daily improved power output, sprint performance, and reduced fatigue during resistance training.
Effect of betaine supplementation on plasma homocysteine and other cardiovascular disease (CVD) risk factors in healthy persons
Olthof MR, Verhoef P
Betaine supplementation at 4-6g daily significantly lowered plasma homocysteine levels by 1-2 μmol/L in healthy adults without affecting blood pressure or triglycerides.
Betaine supplementation decreases plasma homocysteine in healthy adult participants: a meta-analysis.
Olthof MR, Van Vliet T, Boekhoorn-van der Vliet AC, Verhoef P
Meta-analysis of randomized trials showed betaine at up to 4g daily reduced homocysteine concentrations in healthy adults, supporting cardiovascular risk reduction.
Betaine supplementation decreases plasma homocysteine in healthy adult participants: a meta-analysis.
Olthof MR, Van Vliet T, Boekhoorn-van der Vliet AC, Verhoef P
Meta-analysis of randomized trials showed betaine at up to 4g daily reduced homocysteine concentrations in healthy adults, supporting cardiovascular risk reduction.
Effect of betaine supplementation on plasma homocysteine and other cardiovascular disease (CVD) risk factors in healthy persons
Olthof MR, Verhoef P
Betaine supplementation at 4-6g daily significantly lowered plasma homocysteine levels by 1-2 μmol/L in healthy adults without affecting blood pressure or triglycerides.
Dietary choline and betaine intakes in relation to concentrations of inflammatory markers in healthy adults: the ATTICA study (2001-2002)
Detopoulou P, Panagiotakos DB, Antonopoulou S, et al.
Cross-sectional study of healthy adults showed intakes above 360mg TMG daily associated with 19% lower CRP and 12% lower TNF-alpha levels.
Effect of 6 weeks' betaine supplementation on performance in trained male athletes
Cholewa JM, Guimarães-Ferreira L, Zanchi NE
Randomized trial in 23 healthy trained male athletes showed 2.5g TMG twice daily improved power output, sprint performance, and reduced fatigue during resistance training.
Effect of 6 weeks' betaine supplementation on performance in trained male athletes
Cholewa JM, Guimarães-Ferreira L, Zanchi NE
Randomized trial in 23 healthy trained male athletes showed 2.5g TMG twice daily improved power output, sprint performance, and reduced fatigue during resistance training.
Effect of 6 weeks' betaine supplementation on performance in trained male athletes
Cholewa JM, Guimarães-Ferreira L, Zanchi NE
Randomized trial in 23 healthy trained male athletes showed 2.5g TMG twice daily improved power output, sprint performance, and reduced fatigue during resistance training.
Reported Side Effects
Long-term betaine supplementation influences metabolism in the context of a Western-style diet: a randomized placebo-controlled trial in healthy subjects
Gao X, et al.
Six-month RCT in 42 healthy overweight adults found 6g daily TMG increased LDL cholesterol and triglycerides but no other adverse effects.
Research (5 studies)
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