Beta
Metformin ER
medicationExtended-release metformin for type 2 diabetes. Widely used off-label in longevity protocols for its metabolic and potential anti-aging benefits.
Reported Benefits
Effect of Metformin on Obese and Overweight Adults
Clinical research team
Clinical trial examining the effect of metformin combined with a low-calorie diet on metabolic outcomes in obese and overweight adults with increased waist circumference.
Metformin for the Treatment of Insulin Resistance in Women with Stage I-III Breast Cancer Completing Chemotherapy
City of Hope Comprehensive Cancer Center
Phase III randomized controlled trial evaluating extended-release metformin's ability to normalize glycosylated hemoglobin in breast cancer survivors with insulin resistance. Study also investigates metformin's effects on epigenetic changes and inflammatory cytokines.
Metformin in therapeutic applications in human diseases
Multiple authors
Comprehensive review demonstrating that metformin reduces cardiovascular events by 39% in type 2 diabetes patients and provides sustained 33% reduction in myocardial infarction risk over 10 years. Study also documents metformin's effects on inflammation and potential anticancer mechanisms.
COVID-OUT Clinical Trial: Metformin for COVID-19 Treatment
University of Minnesota
Large rigorous clinical trial demonstrating that metformin reduced emergency room visits, hospitalization, or death from COVID-19 by 42%, with over 50% reduction in serious outcomes when taken immediately after symptom onset.
Metformin for the Treatment of Insulin Resistance in Women with Stage I-III Breast Cancer Completing Chemotherapy
City of Hope Comprehensive Cancer Center
Phase III randomized controlled trial evaluating extended-release metformin's ability to normalize glycosylated hemoglobin in breast cancer survivors with insulin resistance. Study also investigates metformin's effects on epigenetic changes and inflammatory cytokines.
Effect of Metformin on Obese and Overweight Adults
Clinical research team
Clinical trial examining the effect of metformin combined with a low-calorie diet on metabolic outcomes in obese and overweight adults with increased waist circumference.
Metformin for the Treatment of Insulin Resistance in Women with Stage I-III Breast Cancer Completing Chemotherapy
City of Hope Comprehensive Cancer Center
Phase III randomized controlled trial evaluating extended-release metformin's ability to normalize glycosylated hemoglobin in breast cancer survivors with insulin resistance. Study also investigates metformin's effects on epigenetic changes and inflammatory cytokines.
Metformin Effects on Cardiovascular Health in Diabetic Patients with Heart Failure
Larsen et al.
Study of 304 diabetic patients with chronic heart failure showed that 3 months of metformin treatment (1000 mg twice daily) significantly reduced myocardial oxygen uptake by 17%, with better myocardial efficiency in patients with higher plasma metformin concentrations.
Metformin in therapeutic applications in human diseases
Multiple authors
Comprehensive review demonstrating that metformin reduces cardiovascular events by 39% in type 2 diabetes patients and provides sustained 33% reduction in myocardial infarction risk over 10 years. Study also documents metformin's effects on inflammation and potential anticancer mechanisms.
Metformin in therapeutic applications in human diseases
Multiple authors
Comprehensive review demonstrating that metformin reduces cardiovascular events by 39% in type 2 diabetes patients and provides sustained 33% reduction in myocardial infarction risk over 10 years. Study also documents metformin's effects on inflammation and potential anticancer mechanisms.
No side effects tracked yet
No side effects have been reported by studies or users for this habit yet.
Related health conditions
Research showing how this habit affects specific health conditions. Always consult healthcare professionals.
May Help With
Hypertension — elevated blood pressure requiring management
Metformin in therapeutic applications in human diseases
Multiple authors
Comprehensive review demonstrating that metformin reduces cardiovascular events by 39% in type 2 diabetes patients and provides sustained 33% reduction in myocardial infarction risk over 10 years. Study also documents metformin's effects on inflammation and potential anticancer mechanisms.
Metformin Effects on Cardiovascular Health in Diabetic Patients with Heart Failure
Larsen et al.
Study of 304 diabetic patients with chronic heart failure showed that 3 months of metformin treatment (1000 mg twice daily) significantly reduced myocardial oxygen uptake by 17%, with better myocardial efficiency in patients with higher plasma metformin concentrations.
Metabolic disorder characterized by high blood sugar
Metformin in therapeutic applications in human diseases
Multiple authors
Comprehensive review demonstrating that metformin reduces cardiovascular events by 39% in type 2 diabetes patients and provides sustained 33% reduction in myocardial infarction risk over 10 years. Study also documents metformin's effects on inflammation and potential anticancer mechanisms.
Research (5 studies)
Community updates
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Stats
Notable users
· Evening (skips on heavy exercise days)
· Evening