Beta
Melatonin
supplementMelatonin regulates the sleep-wake cycle.
Reported Benefits
Long-term use of melatonin supplements to support sleep may have negative health effects
American Heart Association Newsroom
Long-term melatonin use (12+ months) in adults with insomnia was associated with 90% higher risk of incident heart failure over 5 years compared to non-users.
What do we (need to) know about the melatonin in crustaceans?
NCCIH Staff
Melatonin improved jet lag symptoms in travelers, reduced sleep onset time by 22-34 minutes in delayed sleep-wake phase disorder, and enhanced sleep in children.
Melatonin supplementation and human health: a systematic review of randomized trials and meta-analyses
Various (review article)
Melatonin at 2mg extended-release improved MMSE scores, daily activities, and sleep efficiency in adults with mild cognitive issues; 0.15 mg/kg for 6 months increased brain volume measures in older adults.
Melatonin Relieves Neuropathic Pain and Depressive-Like Behaviors by Inhibiting the ERK/NF-κB/c-Fos Signaling Pathway in the Spinal Cord of Spared Nerve Injury Mice.
Mayo Clinic Staff
Melatonin reduces time to fall asleep in adults with delayed sleep phase and jet lag, with clearer benefits for older adults experiencing insomnia.
How Does Melatonin Work?
Cleveland Clinic Staff
Melatonin regulates the sleep-wake cycle in healthy individuals, promoting tiredness at night and wakefulness after rest.
What do we (need to) know about the melatonin in crustaceans?
NCCIH Staff
Melatonin improved jet lag symptoms in travelers, reduced sleep onset time by 22-34 minutes in delayed sleep-wake phase disorder, and enhanced sleep in children.
Melatonin Relieves Neuropathic Pain and Depressive-Like Behaviors by Inhibiting the ERK/NF-κB/c-Fos Signaling Pathway in the Spinal Cord of Spared Nerve Injury Mice.
Mayo Clinic Staff
Melatonin reduces time to fall asleep in adults with delayed sleep phase and jet lag, with clearer benefits for older adults experiencing insomnia.
How Does Melatonin Work?
Cleveland Clinic Staff
Melatonin regulates the sleep-wake cycle in healthy individuals, promoting tiredness at night and wakefulness after rest.
What do we (need to) know about the melatonin in crustaceans?
NCCIH Staff
Melatonin improved jet lag symptoms in travelers, reduced sleep onset time by 22-34 minutes in delayed sleep-wake phase disorder, and enhanced sleep in children.
Melatonin Relieves Neuropathic Pain and Depressive-Like Behaviors by Inhibiting the ERK/NF-κB/c-Fos Signaling Pathway in the Spinal Cord of Spared Nerve Injury Mice.
Mayo Clinic Staff
Melatonin reduces time to fall asleep in adults with delayed sleep phase and jet lag, with clearer benefits for older adults experiencing insomnia.
Reported Side Effects
Long-term use of melatonin supplements to support sleep may have negative health effects
American Heart Association Newsroom
Long-term melatonin use (12+ months) in adults with insomnia was associated with 90% higher risk of incident heart failure over 5 years compared to non-users.
Related health conditions
Research showing how this habit affects specific health conditions. Always consult healthcare professionals.
May Help With
Difficulty falling asleep, staying asleep, or waking too early
Melatonin Relieves Neuropathic Pain and Depressive-Like Behaviors by Inhibiting the ERK/NF-κB/c-Fos Signaling Pathway in the Spinal Cord of Spared Nerve Injury Mice.
Mayo Clinic Staff
Melatonin reduces time to fall asleep in adults with delayed sleep phase and jet lag, with clearer benefits for older adults experiencing insomnia.
What do we (need to) know about the melatonin in crustaceans?
NCCIH Staff
Melatonin improved jet lag symptoms in travelers, reduced sleep onset time by 22-34 minutes in delayed sleep-wake phase disorder, and enhanced sleep in children.
Research (5 studies)
Community updates
No updates yet for this supplement.
Be the first to share your experience!
