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Spermidine
supplementSpermidine activates autophagy for cellular renewal.
Reported Benefits
Spermidine-Rich Foods and Their Anti-Aging Benefits
Not specified
A randomized controlled trial in older adults aged 60-80 reported improved memory performance and mnemonic discrimination after three months of 1.2 mg daily spermidine supplementation, with follow-up confirming sustained cognitive benefits and no adverse effects.
Correction: Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)-study protocol for a randomized controlled trial.
Not specified
Phase II randomized, double-blind, placebo-controlled trial showed daily 1.2 mg spermidine supplementation for three months improved cognitive function in older adults with subjective cognitive decline, with high compliance and no changes in vital signs or blood parameters.
Spermidine-Rich Foods and Their Anti-Aging Benefits
Not specified
A randomized controlled trial in older adults aged 60-80 reported improved memory performance and mnemonic discrimination after three months of 1.2 mg daily spermidine supplementation, with follow-up confirming sustained cognitive benefits and no adverse effects.
Correction: Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline (SmartAge)-study protocol for a randomized controlled trial.
Not specified
Phase II randomized, double-blind, placebo-controlled trial showed daily 1.2 mg spermidine supplementation for three months improved cognitive function in older adults with subjective cognitive decline, with high compliance and no changes in vital signs or blood parameters.
Spermidine delays aging in humans.
Jansen-Dürr P
Two prospective population-based studies using food questionnaires showed higher nutritional spermidine uptake independently associated with reduced overall, cardiovascular, and cancer-related mortality in humans after adjusting for confounders.
Spermidine in health and disease
Madeo F, et al.
Epidemiological studies correlate elevated dietary polyamine uptake, including spermidine, with reduced cardiovascular and cancer-related mortality in humans.
Spermidine delays aging in humans.
Jansen-Dürr P
Two prospective population-based studies using food questionnaires showed higher nutritional spermidine uptake independently associated with reduced overall, cardiovascular, and cancer-related mortality in humans after adjusting for confounders.
Spermidine in health and disease
Madeo F, et al.
Epidemiological studies correlate elevated dietary polyamine uptake, including spermidine, with reduced cardiovascular and cancer-related mortality in humans.
No side effects tracked yet
No side effects have been reported by studies or users for this habit yet.
Research (4 studies)
Community updates
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